Big Hat Biosciences

Overview

Big Hat Biosciences is an AI-driven protein and antibody design company. Co-founded by Peyton Greenside (CEO), the company's core competitive advantage lies in fast lab-in-the-loop data generation — the ability to rapidly produce high-quality experimental data that feeds back into model training. Big Hat has demonstrated that data quality matters as much as quantity: by quality-filtering datasets down to 25% of their original size, the company achieved better model outcomes than with the full unfiltered data.

Big Hat Biosciences partners with Lilly Tune Lab for dataset sharing and presents research at ICLR, a leading machine learning conference. The company has built an internal platform that matches design problems to optimal dataset-model pairs, reflecting a systematic approach to scientific AI development grounded in the insight that compute is not the bottleneck — data generation speed is.